Doug McDonald Ancestry Analysis

As I noted last time, I was in a situation where I needed some help into ascertaining my genetic ancestry. Fortunately, there are people willing to do that sort of analysis for you. One of these is Doug McDonald. So I sent him my data and within an hour I had an analysis.

The PCA plot below shows me as a large cross in relation to different reference populations (like Europeans, Africans, East Asians etc).

Doug McDonald Ancestry Plot for me

Here’s what he said:

We also do quantitative tests. These come in three flavors, first without South Asia (represented by Pakistan) and the Mideast, second with South Asia, and finally with all three, as comparison panels.

The typical random error in the data (standard deviation) is 1%, meaning that numbers less than about 2% are not highly significant. There are also systematic errors. In particular, there is cross-coupling of values for Europe, the Mideast and S. Asia. For example, on the middle panel, a pure, northwestern European measures about 9% S. Asian, and on the third panel they typically measure 4.5% Mideastern and 8% S. Asian. Actual people from South Asia or the Mideast always test at least 15% European.

His first panel:

Europe 71.1%
East Asia 12.3%
Africa 8.2%
Oceania 4.7%
America 3.3%

When South Asia is added:

South Asia 48.7%
Europe 36.8%
Africa 5.8%
East Asia 5.0%
Oceania 2.4%
America 1.2%

And finally when Middle East is added to the list:

South Asia 46.9%
Europe 29.0%
Mideast 11.0%
East Asia 5.1%
Africa 4.3%
Oceania 2.3%
America 1.4%

And here is his analysis of these results:

This is basically a person from somewhere in region from say Iraq to Pakistan, with a substantial African contribution. The East Asian is probably not real. The African could be a few percent direct recent admixture, or it could be in input from a previously mixed population like the Makrani of Pakistan. My techniques can’t tell them apart.

The most interesting thing here for me was the African percentage.

Author: Zack

Dad, gadget guy, bookworm, political animal, global nomad, cyclist, hiker, tennis player, photographer

One thought on “Doug McDonald Ancestry Analysis”

Comments are closed.