Genetics and Health

When the doctor told me I had Ureterolithiasis, I logged into 23andme to check my genetic risk. There was only one SNP (rs4293393) listed there. The G allele increased the risk 14% but I have AA, so typical odds. Next step was checking SNPedia where I found 8 SNPs, of which some are given below.… Continue reading Genetics and Health

Punjabi and What?

Looking at the admixture analysis for my Harappa Ancestry Project, I count 6 Punjabis (not including my sister and I). Let’s average those six and compare them to me and my sister. Ancestral Pop Average Punjabi Me My sister NSA1 NSA2 South Asian 46% 38% 35% 7% 7% Balochistan/Caucasus 35% 35% 34% 32% 30% Kalash… Continue reading Punjabi and What?

Harappa Clustering

As I had computed the admixture percentages for myself, my sister and other participants in my Harappa Ancestry Project, I decided to do some clustering analysis on them to see which persons clustered together. The resulting tree for a hierarchical clustering is as follows. It shows which persons are the most similar. I am HRP0001… Continue reading Harappa Clustering

My Harappa Project Results

I have been blogging up a storm on Harappa Ancestry Project with more than 50 posts since I last linked to it. Let’s see what I have found out about myself there. Here are the admixture results for me and my sister: Me My sister South Asian 37.9% 34.8% Balochistan/Caucasus 34.7% 34.2% Southwest Asian 9.8%… Continue reading My Harappa Project Results

Your Genes, Regulated?

The FDA had a meeting the last two days: FDA is convening this two-day meeting to seek the Panel’s expert opinion and input on scientific issues concerning Direct to Consumer (DTC) genetic tests that make medical claims. This meeting is focused specifically on issues regarding clinical genetic tests that are marketed directly to consumers (DTC… Continue reading Your Genes, Regulated?

Eurogenes

Davidski of Eurogenes is also a genome blogger. In his admixture analysis for West, South and Central Asians, I am PKEG1 and my results are as follows: European 4% Siberian 1% Caucasus 32% Sub-Saharan African 4% Middle Eastern 9% East Asian 1% South Asian 50% Here’s a chart showing some of the reference samples and… Continue reading Eurogenes

Dodecad Project II

I talked about the Dodecad Project last time. Dienekes also did some cluster analysis using mclust. When he classified everybody into 48 clusters, I showed up almost all alone in cluster 21. Only one other member who is a Bihari Brahmin had a 50% chance of belonging in my cluster. With 56 clusters, I am… Continue reading Dodecad Project II