As I have mentioned before, cousin marriages were fairly common among my family. My parents are first cousins. So are my father’s parents. My mother’s parents are second cousins once removed. So instead of 32 great-great-great grandparents, I have only about 18. Since my wife and I are not related, I wondered how my inbred… Continue reading Outbreeding Works in a Single Generation
Zack Ajmal Phased Genome
A few months ago, I made my DNA genotyping results from 23andme public. Since I got results for both my parents as well, I have now used BEAGLE to phase my genetic data. In simple words, I have been able to separate the contribution of my Dad and my Mom on my DNA. I am… Continue reading Zack Ajmal Phased Genome
Family DNA Results
I posted my genetic ancestry results. Now, we’ve got my parents, my sister and my wife tested with 23andme. So I thought a comparison would be interesting. Here’s the ancestry painting from 23andme which uses three reference populations: Yoruba from Nigeria, Chinese and Japanese, and Utahns of Northwestern European descent. Dad Mom Sister Me Wife… Continue reading Family DNA Results
Genome in the Wild
I tested with 23andme in April 2010 and then upgraded to their version 3 chip with almost a million SNPs last Christmas. Now I am releasing my personal genome in the public domain. To the extent possible under law, Zack Ajmal has waived all copyright and related or neighboring rights to Zack Ajmal 23andme v3… Continue reading Genome in the Wild
Dodecad has come up with a new version (v3) of its admixture results. Here are my results: South Asian 37.4% West Asian 23.3% Mediterranean 9.8% West European 9.6% Southwest Asian 6.2% East European 3.5% Southeast Asian 2.4% East African 2.2% Northeast Asian 1.9% Northwest African 1.5% Neo African 1.1% Palaeo African 1.0% Dodecad also has… Continue reading Dodecad Oracle
Genetics and Health
When the doctor told me I had Ureterolithiasis, I logged into 23andme to check my genetic risk. There was only one SNP (rs4293393) listed there. The G allele increased the risk 14% but I have AA, so typical odds. Next step was checking SNPedia where I found 8 SNPs, of which some are given below.… Continue reading Genetics and Health
Punjabi and What?
Looking at the admixture analysis for my Harappa Ancestry Project, I count 6 Punjabis (not including my sister and I). Let’s average those six and compare them to me and my sister. Ancestral Pop Average Punjabi Me My sister NSA1 NSA2 South Asian 46% 38% 35% 7% 7% Balochistan/Caucasus 35% 35% 34% 32% 30% Kalash… Continue reading Punjabi and What?
As I had computed the admixture percentages for myself, my sister and other participants in my Harappa Ancestry Project, I decided to do some clustering analysis on them to see which persons clustered together. The resulting tree for a hierarchical clustering is as follows. It shows which persons are the most similar. I am HRP0001… Continue reading Harappa Clustering
My Harappa Project Results
I have been blogging up a storm on Harappa Ancestry Project with more than 50 posts since I last linked to it. Let’s see what I have found out about myself there. Here are the admixture results for me and my sister: Me My sister South Asian 37.9% 34.8% Balochistan/Caucasus 34.7% 34.2% Southwest Asian 9.8%… Continue reading My Harappa Project Results
Your Genes, Regulated?
The FDA had a meeting the last two days: FDA is convening this two-day meeting to seek the Panel’s expert opinion and input on scientific issues concerning Direct to Consumer (DTC) genetic tests that make medical claims. This meeting is focused specifically on issues regarding clinical genetic tests that are marketed directly to consumers (DTC… Continue reading Your Genes, Regulated?