Genetics and Health

When the doctor told me I had Ureterolithiasis, I logged into 23andme to check my genetic risk. There was only one SNP (rs4293393) listed there. The G allele increased the risk 14% but I have AA, so typical odds.

Next step was checking SNPedia where I found 8 SNPs, of which some are given below.

rs219780 (23andme): The high risk is CC but I wasn’t genotyped at this location. Also, CC is the most common, so it is quite likely that I have that.

rs219778 (23andme): Carriers of TT have a slightly increased risk and that’s what I have.

rs9310709 (23andme): Risk allele is C and I have CC.

rs10941694: I was not genotyped.

rs13070584: I was not genotyped.

More important than these though is the simple fact that my Dad had it too. Thus if there is a genetic association, I am likely to be higher than typical risk.

Author: Zack

Dad, gadget guy, bookworm, political animal, global nomad, cyclist, hiker, tennis player, photographer