Eurogenes

Davidski of Eurogenes is also a genome blogger. In his admixture analysis for West, South and Central Asians, I am PKEG1 and my results are as follows: European 4% Siberian 1% Caucasus 32% Sub-Saharan African 4% Middle Eastern 9% East Asian 1% South Asian 50% Here’s a chart showing some of the reference samples and… Continue reading Eurogenes

Dodecad Project II

I talked about the Dodecad Project last time. Dienekes also did some cluster analysis using mclust. When he classified everybody into 48 clusters, I showed up almost all alone in cluster 21. Only one other member who is a Bihari Brahmin had a 50% chance of belonging in my cluster. With 56 clusters, I am… Continue reading Dodecad Project II

Dodecad Ancestry Project

I asked Dienekes to include me in his Dodecad Ancestry Project and he gave me the following results: Ancestral Component Percentage South Asian 44.9% West Asian 33.7% Southwest Asian 5.7% North European 5.5% South European 3.7% East African 3.4% Northwest African 2.1% West African 0.6% East Asian 0.4% Northeast Asian 0.1% You can see the… Continue reading Dodecad Ancestry Project

McDonald Ancestry Analysis II

When my sister got her 23andme results, we sent them over to Doug McDonald. I was expecting something close to my results, but it was radically different: This one is different it says 37% Druze, 4% Bushman or Pygmy, the rest North India. It is complicated enough that the program refuses to generate a spot… Continue reading McDonald Ancestry Analysis II

Doug McDonald Ancestry Analysis

As I noted last time, I was in a situation where I needed some help into ascertaining my genetic ancestry. Fortunately, there are people willing to do that sort of analysis for you. One of these is Doug McDonald. So I sent him my data and within an hour I had an analysis. The PCA… Continue reading Doug McDonald Ancestry Analysis

Genome Similarity

23andme has a feature where you can find out how similar your genes are to your friends and family (who you are sharing with at the site). The result is a bar list with percentages showing similarity. The number next to each person in the bar list is a measure of similarity. Specifically, it is… Continue reading Genome Similarity

My Biogeographical Ancestry

There are several different ways to figure out your genetic ancestry. One way that 23andme shows your ancestry is by comparison with reference populations of the HGDP (Human Genome Diversity Project) dataset. I have listed how similar I am to various groups in the table below: Reference Population Similarity Groups Included Central & South Asians… Continue reading My Biogeographical Ancestry

Ancestry Painting

23andme has a feature called ancestry painting which gives you the percentages of different populations you are admixed from. In my case, I got the following: European 91.22% Asian 8.69% African 0.09% Ignore the precision (to 2 decimal places). I showed that because I wanted to highlight the nonzero African ancestry percentage which I will… Continue reading Ancestry Painting

Paternal and Maternal Lines

We men inherit the Y chromosome from our fathers who got it from their fathers. So the Y chromosome can be used to trace your paternal lineage. Different sequences of alleles and mutations can be assigned to haplogroups where a haplogroup signifies common descent on the uniparental line. According to my 23andme results, I belong… Continue reading Paternal and Maternal Lines

Inbreeding

I have found out I am actually from West Virginia. Ok, I am just joking. I knew that my family had a history of marriages among relatives. After all I have only 10 great-great-grandparents instead of the usual 16. With my genome in hand, I set about to quantify the inbreeding. First, I used David… Continue reading Inbreeding